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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
19.09
Human Site:
T718
Identified Species:
35
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
T718
P
E
R
R
E
V
V
T
L
R
C
N
H
R
D
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
S681
R
Y
Q
G
P
Y
V
S
M
A
F
I
T
V
L
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
F684
G
P
Y
V
S
M
A
F
I
T
V
L
K
M
V
Dog
Lupus familis
XP_541867
872
95696
T718
P
E
R
R
E
V
V
T
L
R
C
N
H
R
D
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
T718
P
E
R
R
E
V
V
T
L
R
C
N
H
R
D
Rat
Rattus norvegicus
P31421
872
95755
T718
P
E
R
R
E
V
V
T
L
R
C
N
H
R
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
T718
P
E
R
R
E
V
V
T
L
R
C
N
H
G
D
Chicken
Gallus gallus
XP_416842
879
98936
I727
P
E
K
R
E
T
V
I
L
K
C
N
V
K
D
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
L712
V
Q
T
E
S
I
L
L
E
C
N
E
G
F
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
I775
Y
P
D
R
R
E
V
I
L
K
C
K
I
Q
D
Honey Bee
Apis mellifera
NP_001011624
933
103448
I754
Y
P
D
R
K
Q
V
I
L
K
C
N
I
Q
D
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
V828
Y
P
T
R
D
Q
V
V
L
T
C
N
V
P
D
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
I1300
A
E
D
R
S
E
A
I
L
K
C
G
I
T
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
6.6
0
100
N.A.
100
100
N.A.
93.3
60
N.A.
0
N.A.
33.3
40
40
26.6
P-Site Similarity:
100
26.6
13.3
100
N.A.
100
100
N.A.
93.3
80
N.A.
20
N.A.
46.6
60
46.6
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
16
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
77
0
0
0
0
% C
% Asp:
0
0
24
0
8
0
0
0
0
0
0
0
0
0
70
% D
% Glu:
0
54
0
8
47
16
0
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% F
% Gly:
8
0
0
8
0
0
0
0
0
0
0
8
8
8
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
39
0
0
% H
% Ile:
0
0
0
0
0
8
0
31
8
0
0
8
24
0
0
% I
% Lys:
0
0
8
0
8
0
0
0
0
31
0
8
8
8
0
% K
% Leu:
0
0
0
0
0
0
8
8
77
0
0
8
0
0
8
% L
% Met:
0
0
0
0
0
8
0
0
8
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
62
0
0
0
% N
% Pro:
47
31
0
0
8
0
0
0
0
0
0
0
0
8
0
% P
% Gln:
0
8
8
0
0
16
0
0
0
0
0
0
0
16
0
% Q
% Arg:
8
0
39
77
8
0
0
0
0
39
0
0
0
31
0
% R
% Ser:
0
0
0
0
24
0
0
8
0
0
0
0
0
0
0
% S
% Thr:
0
0
16
0
0
8
0
39
0
16
0
0
8
8
0
% T
% Val:
8
0
0
8
0
39
77
8
0
0
8
0
16
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
24
8
8
0
0
8
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _